Since its foundation in 1946, TCI’s philosophy has been to contribute to society through the manufacturing and supply of organic laboratory chemicals. We are proud, that today our company offers more than 30,000 quality reagents on a global basis. In recent years, our business has also expanded to the manufacturing of fine chemicals such as pharmaceutical and cosmetic raw materials, electroluminescent compounds, and building blocks for liquid crystals.
Recently, several oligonucleotide drugs have been approved and are being used in clinical applications. Oligonucleotide drugs are generally composed of about 20 nucleotides, but the natural oligonucleotide structure is not suitable for drugs from the perspectives of biostability and affinity to the target. Therefore, chemically modified oligonucleotides are synthesized and utilized as drug candidates.
TCI presents here the phosphoramidite method and introduces you to a variety of Reagents like nucleoside phosphoramidites, condensation activators, sulfur-transfer reagents and deprotection reagents used within this method.
For more information: Oligonucleotide Synthesis Reagents | Tokyo Chemical Industry UK Ltd. (tcichemicals.com)
Tokyo Chemical Industry UK Ltd.
The Magdalen Centre
Robert Robinson Avenue
The Oxford Science Park,
Oxford OX4 4GA
Tel: 01865 784560
You can also contact our local sales representative Mr. Robbie Benning: Robbie.Benning@TCIchemicals.com