Immetacyte Limited - GMP Cell Therapy Technician

Job Title:
GMP Cell Therapy Technician
Technical roles
Closing Date:

GMP Cell Therapy Technician

Location: Manchester, UK

Position reports to: GMP Production Manager

Competitive Salary and Benefits Package

Application Deadline: 28th February 2020

About the Company:

Immetacyte Ltd is focused on developing patient specific immunotherapy, allowing the patient’s own immune system to be harnessed in order to fight cancers. Specifically, Immetacyte is developing adoptive cell therapy (ACT) and has expertise in manufacturing and engineering of cells in a GMP compliant manner ready for patient infusion. The company has a track record of developing cell therapies with clinical success. Immetacyte is beginning clinical trials in its autologous cell therapy product Tumour Infiltrating Lymphocytes (TIL).

The Opportunity:

We are therefore pleased to offer an excellent opportunity to join this early stage SME at a dynamic and exciting time in the evolution of the company. We are seeking to appoint a diligent, enthusiastic and motivated individual to the following post.

The Key Tasks detailed within this Job Description are not intended to represent an exhaustive list of the duties that the job holder may be required to undertake and where reasonable the employer may from time to time ask for activities in addition to this job role

Main Duties and Responsibilities

The post holder will be required to:

  • Perform GMP (Good Manufacturing Process) cell culture and the associated GMP assays within a laboratory, clean room or Aseptic Isolator
  • Undertake validation studies of processes and equipment as required
  • Perform standard operating policies & procedures (SOP’s) and novel technology transfer processes, including state of the art techniques developed in cell culture, flow cytometry and a range of biological assays
  • Produce and review technical documentation (SOPs, MPDs, etc) as part of the CTL quality system
  • Clearly and accurately record/transcribe and communicate translational & GxP procedures
  • Perform critical checks of the records of fellow staff and external contractors/suppliers
  • Be aware of the regulatory requirements (GMP, GCP etc) relevant to CTL and to ensure compliance with the regulations
  • Prepare materials and reagents as required
  • Order equipment & consumables and perform routine stock checks to maintain levels of critical stock, as well as communicating with suppliers and sourcing new consumables/equipment as required
  • Perform routine operation, testing and maintenance checks of laboratory equipment
  • Arrange for equipment calibration, maintenance and repair with external contractors
  • Ensure critical samples are safely delivered to external testing facilities
  • Perform laboratory housekeeping including COSHH and Risk assessments
  • Carry out regular facility cleaning, monitoring and disposal of waste.

Skills & Experience

Essential Requirements:

  • A graduate degree level in a biological science related discipline
  • A basic knowledge of biomedicine and practical experience in cell biology and the associated assays
  • Experience of working within a group whilst also maintaining individual responsibility with minimal active management
  • Evidence of professional development within the field of biomedical science by demonstrating an active career path
  • Flexible approach to working
  • Special Skills Requirements
  • Good time management skills
  • Excellent communication skills – written and oral
  • Work well with others in a team environment
  • Ability to develop and maintain good working relationships with co workers and supervisors
  • Excellent IT skills
  • Attention to detail and accuracy of both written and activities performed


Desirable Skills:

Previous experience in:

  • Cell therapy
  • Immunotherapy
  • Biomedicine
  • Genetic/protein engineering
  • Flow cytometry
  • Professional Registration in an appropriate subject area
  • GMP, Quality Control or quality assurance in the field of Biomedicine or related field
  • Understanding of the role of the MHRA, HTA and H&SE in Good Manufacturing Practice
  • Organisational skills demonstrating an ability to perform complex multistage procedures within a group and as an individual

Application Process: 

Please send a CV and a detailed covering letter to or to the address below.
Immetacyte Ltd
48 Grafton Street
M13 9XX

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